Not knowing which aspect of caution you’re concerned about…but applied in context (of being a coil killer), IMO it’s just something that you kind of have to accept as it comes with the territory. Otherwise, you’re going to lose access to a lot of great flavors that you’d otherwise enjoy! (chocolates for instance)
Now, if sucralose is the primary concern, then that’s a whole 'nother issue.
I also understand if you’re talking about it being a concern from the standpoint of if you are still buying pre-made/retail replacement coils.
But if you’re building your own, it’s a very small price to pay, and given that you can pull the cotton and dry burn most coil wire types clean… There’s really no reason at all to be worried about gunk. Since dry burning extends the life of the coil, you’re still cutting your wire usage in half even if you only dry burn once before you install a fresh coil!
I’m guessing here, but I take it you’re still buying pre-made coils? (Might be time to make the leap in gear if you are! -besides which, it’s cheaper!)