I had a tingling and numbness in my hands going up my arms the very moment I opened the bottle of nic base. Can breathing it cause a reaction? Wore gloves, and I think I may have touched a syringe without gloves later on but was feeling affected long before that point.
2 Likes
What is your definition of âbreathing itâ? Were you sniffing it or just in the same room? Iâve never heard of anyone having a reaction like that just by opening the bottle. And just touching a syringe is hardly going to cause any real problems either. The nic (assuming itâs high strength) would need to have been absorbed through the epidermis.
3 Likes
Hi David,
I just went to mix a couple things this afternoon and as soon as I opened the bottle of nic (120ml bottle labeled as 60mg) and I started feeling symptoms of OD, like the tingley hands, rushy, etc. Can it effect you by being breathed in? During the rest of the process I may have touched a syringe ungloved that I touched with the gloves, but I had already been feeling the effect at this point. I feel better now, after 3hrs I think
2 Likes
@DRG413 It sounds to me like you were already building up nic in your system, and going to mix was just coincidental timing.
At 60mg not very likely (unless you were directly inhaling it ie: VAPING IT). Even at 100mg, Iâve never read about such things occurring. (though itâs not to say itâs impossible. I guess with the right âminimum body weightâ etc, âanything could happenââŚ)
Now you could get some slight tingling on whatever part of the body that came into contact with 60mg, but even then, it wouldnât be âthe instantâ you opened the bottle, nor the instant it touched your skin. It takes a little while for the skin to react. Not an instant âoh shitâ reaction, like there would be with something like hydrochloric or sulfuric acid, or fireâŚ
While a head-spin or worse (Nic overdose) will definitely fray the nerves, and is definitely something to always be mindful of, I think youâre ok. (âI feel better now, after 3hrsâ)
But given the concern youâre having, it would seem like a good idea if you stay with the 60mg nic (and not 72 or 100mg), until you get more comfortable with handling it.
Even if you need to step down from 60mg (for your own piece of mind) thereâs no shame or harm in doing so. Itâs all about being in your comfort zone. Not just âgoing with the herdâ because others are doing it! 
Be well, be comfortable, and above all, be safe for your conditions and needs!
5 Likes
Ok thanks. I called poison control when I was feeling really rushy and they asked me what strength. The bottle says 60mg. Itâs a 120ml bottle. Does that mean itâs 60mg/ml orâŚ? And just to clarify with this base, to make a 30ml juice at 6mg/ml I put 3ml of the nic base right?
2 Likes
That means:
You have a quantity of 120ml (milliliters) at a strength of 60mg/mL.
Thatâs correct.
4 Likes
I use 250mg and have gotten it on my skin and never had a problem, finish my mix and the rinse off hand,or arm. You have to be hypersensitive to have a reaction from 60ml. David already gave you sound advice.
5 Likes
@DRG413 please try to avoid cross posting the same post in multiple threads it makes it harder for people to answer you. I have moved the other posts in here
6 Likes
Iâve had my hands itch after handling it, but even then Iâm not sure itâs not coincidental. Nothing I choose to worry about.
6 Likes
I guess just standing over the open bottle on the counter. The smell was pretty strong.
2 Likes
Sorry, was all revved up and kinda wanting to cast asany lines as possible. I was pretty freaked out.
4 Likes
Are you sure thatâs a bottle of nicotine? Because liquid nicotine is odorless for the most part.
4 Likes
Itâs a VG base.
1 Like
LOLâŚok, but VG is odorless as well. And it wouldnât make the bottle smell.
4 Likes
Hmmmm. Weird. I ordered it in a kit from a semi local website. Was supposed to include instructions actually but didnât. Suppose thatâs kinda dodgy.
2 Likes
There ya go! I will refrain from further comment.
3 Likes
I have tried a drop of 100 mg on my tongue, tastes like burning, lol, no side effects were noted.
2 Likes
Been mixing since, I think 2015 or 2016âŚtime goes by fastâŚbut anyways, I have always mixed with 100mg/ml nic and have not had this reaction.
Safety is a relative term, but in general have felt comfortable mixing at that level. But I do take care to not put my nose to the bottle and snif. Knock on wood, I havenât gotten a drop on my hand (that I know of), not have had physical issues.
That being said I donât want to take away from what you experienced. But considering that people vape jull pods with 50mg/ml I kinda think part of an issue is the brain. The mind does some pretty f@ck up things. Hope your feeling better. Drink some water.
4 Likes
VG and PG donât really evaporate rapidly like some other liquids do. Open bottle of VG or PG based nicotine doesnât release fumes. Nicotine itself is not a volatile liquid that evaporates, in fact itâs usually a powder that is dissolved in PG or VG. Even prolonged contact with skin that I had with my 100mg nicotine base never gave me any kind of reaction (talking about skill on my hands) and iâm known to be alergic to quite a few other substances.
My guess is itâs either psychosomatic (you were freaked out from the very fact you were handling nicotine), or a reaction to something entirely different.
As for DiY and safety, starter packs from unknown vendors are best avoided. Look at the resources page on ELR for trusted vendors and get your stuff from there.
10 Likes
Nope 
8 Likes