Coronavirus

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The very thought of that durn Gina vyrus being “bi” makes my manhood pretty plum pie nervous. You ?

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I guess if I had man parts… but who knows… some men do like that sort of thing. :slight_smile:

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Wul, “bi” I can handle when its purty wimen. But you tell that Tom Cottonball fella that we ain’t no “trans”!

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https://www.nydailynews.com/coronavirus/ny-coronavirus-philadelphia-police-drag-bus-face-mask-pandemic-20200411-3sp4idfna5bcpgp43c5snymnga-story.html

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I used to enjoy LivePD, and was happy when it came back on yesterday. Until the second call involved warning a corner store about social distancing. It may be a common thing these days but I get enough of it already. I like to watch silly TV shows to not have to deal with everyday things all the time. I wonder how they can fish on Wicked Tuna being 6 feet apart all the time…

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(Vox, April 11, 2020):

Two studies have some good news and bad news for potential coronavirus treatments - Remdesivir looks “hopeful” but hydroxychloroquine has some worrying side effects

@SessionDrummer

Is it me or is this starting to resemble a police state? I saw something where a police officer said the Constitution wasn’t suspended to a driver he pulled over and that the driver had no rights anymore.

Frightening!!!

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In Denmark a special temporary “Epidemic Law” has suspended part of the constitution.

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I posted on March 29 on what I hoped was a positive, but ended up not being. But it does look now like Missouri is peaked/peaking. Illinois seems similar but with a markedly higher number, because Chicago. Has to be good news…

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(The Guardian, April 11, 2020):

China clamping down on coronavirus research, deleted pages suggest -
Move is likely to be part of attempt to control the narrative surrounding the pandemic

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@Raven-Knightly
Don’t hold me to this but I think I remember Dick Cheney in an interview saying the way to accomplish regime change was to release a virus. Release it in any country so the people feared for their lives Not a massively deadly disease but one but that caused hysteria as the disease s[read through densely populated areas.
This would cause the authorities to demand people separate so they wouldn’t form a resistance The Governor would then order National Guard And local and sate police To seize weapons.
I can’t remember where I heard it but I swear its true.

@Raven-Knightly
Do you believe this might suggest it mutating or that they feel the country’s vulnerable?

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Have a few SARS-CoV-2 variants (note using mouse-over of graphic data that not all are mutations).

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… findings suggest that the virus is evolving and European, North American and Asian strains might coexist, each of them characterized by a different mutation pattern. The contribution of the mutated RdRp to this phenomenon needs to be investigated. To date, several drugs targeting RdRp enzymes are being employed for SARS-CoV-2 infection treatment. Some of them have a predicted binding moiety in a SARS-CoV-2 RdRp hydrophobic cleft, which is adjacent to the 14408 mutation we identified. Consequently, it is important to study and characterize SARS-CoV-2 RdRp mutation in order to assess possible drug-resistance viral phenotypes. It is also important to recognize whether the presence of some mutations might correlate with different SARS-CoV-2 mortality rates. …

… We identified novel mutation hotspots in the SARS-CoV-2 genome sequences. Interestingly, some appeared after February 2020, only in European patients. Among these hotspots, one mutation in position 14408 is located within the RdRp protein and is associated with an overall increased mutation rate. An in silico analysis comparing annotated functional domains of SARS-CoV and SARS-CoV-2 sequences, showed that this particular mutation occurs in the so-called RdRp interface domain, a still poorly characterized surface structure, involved in protein-protein interactions16. The role for the RdRp interface domain requires further investigations, and in particular the effect of mutation in position 14408, its interaction with other cofactors (such as ExoN, nsp7 and nsp8), possibly affecting its proofreading activity and potentially altering its mutation rate. It is also essential to understand if the described mutations could result in the emergence of drug-resistance viral phenotypes. Our data may help the development of diagnostic and therapeutic strategies and to study potential drug resistance mechanisms.

Pre-Print Source (April 11, 2020):

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(SLATE, April 11, 2020):

WHO Investigating Reports of Coronavirus Patients Testing Positive Again After Recovery

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(Scientific American, April 10, 2020):

What Immunity to COVID-19 Really Means - The presence of antibodies to the SARS-CoV-2 virus could provide some protection, but scientists need more data

With some pathogens, such as the varicella-zoster virus (which causes chicken pox), infection confers near-universal, long-lasting resistance. Natural infection with Clostridium tetani, the bacterium that causes tetanus, on the other hand, offers no protection - and even people getting vaccinated for it require regular booster shots. On the extreme end of this spectrum, individuals infected with HIV often have large amounts of antibodies that do nothing to prevent or clear the disease.

At this early stage of understanding the new coronavirus, it is unclear where COVID-19 falls on the immunity spectrum. Although most people with SARS-CoV-2 seem to produce antibodies, “we simply don’t know yet what it takes to be effectively protected from this infection,” says Dawn Bowdish, a professor of pathology and molecular medicine and Canada Research Chair in Aging and Immunity at McMaster University in Ontario. Researchers are scrambling to answer two questions: How long do SARS-CoV-2 antibodies stick around? And do they protect against reinfection?

… although it appears that recovered COVID-19 patients have antibodies for at least two weeks, long-term data are still lacking. So many scientists are looking to other coronaviruses for answers. Immunity to seasonal coronaviruses (such as those that cause common colds), for example, starts declining a couple of weeks after infection. And within a year, some people are vulnerable to reinfection. … studies of SARS-CoV - the virus that causes severe acute respiratory syndrome, or SARS, which shares a considerable amount of its genetic material with SARS-CoV-2 - are more promising. Antibody testing shows SARS-CoV immunity peaks at around four months and offers protection for roughly 2 - 3 years.

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(The Atlantic, April 6, 2020):

What the Racial Data Show - The pandemic seems to be hitting people of color the hardest

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How will their disinfecting affect your fish? ETA: Oh nevermind, I just read your post again and realized I need to go to sleep, lol. Cracking myself up.

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Source: https://i.imgur.com/8fsfvgx.png


Source: https://piximus.net/media2/40457/it-turns-out-that-donald-trumps-mouth-fits-perfectly-on-pufferfish-2.jpg

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(New York Times, April 12, 2020):

Small Chloroquine Study Halted Over Risk of Fatal Heart Complications -
A research trial of coronavirus patients in Brazil ended after patients taking a higher dose of chloroquine, one of the drugs President Trump has promoted, developed irregular heart rates

… infectious disease doctors and drug safety experts said the study provided further evidence that chloroquine and hydroxychloroquine, which are both used to treat malaria, can pose significant harm to some patients, specifically the risk of a fatal heart arrhythmia. Patients in the trial were also given the antibiotic azithromycin, which carries the same heart risk. Hospitals in the United States are also using azithromycin to treat coronavirus patients, often in combination with hydroxychloroquine. … Within three days, researchers started noticing heart arrhythmias in patients taking the higher dose. By the sixth day of treatment, 11 patients had died, leading to an immediate end to the high-dose segment of the trial.

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I am of the opinion that Dick Cheney is himself a form of living, breathing malignant viral pathogen. :thinking:


Source: https://media.salon.com/2014/07/dick_cheney3.jpg

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@Raven-Knightly
I don’t know if I could have been so kind…lol.

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